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• Activity deltas table
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Motif ID: STAT5{A,B}.p2

Z-value: 1.194

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_82674546	2.826		CCDC90B	coiled-coil domain containing 90B
chr11_-_82675024	1.949	NM_021825	CCDC90B	coiled-coil domain containing 90B
chr19_-_49309102	1.557		LOC100379224	hypothetical LOC100379224
chr19_+_49248003	1.431	NM_013361	ZNF223	zinc finger protein 223
chr19_+_49309350	1.390	NM_013362	ZNF225	zinc finger protein 225
chr19_+_49361054	1.260	NM_001146220 NM_001032373 NM_001032374 NM_015919 NM_001032372	ZNF226	zinc finger protein 226
chr19_-_62680703	1.259	NM_001024596 NM_001144068	ZNF772	zinc finger protein 772
chr19_+_49180171	1.023	NM_003445 NM_198089	ZNF155	zinc finger protein 155
chr9_+_129226473	0.960	NM_007135	ZNF79	zinc finger protein 79
chr9_+_129226535	0.949		ZNF79	zinc finger protein 79
chr17_+_36515166	0.924	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr19_+_49290319	0.894	NM_013398	ZNF224	zinc finger protein 224
chr4_+_86615275	0.880	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr7_+_89870707	0.878		CLDN12	claudin 12
chr19_+_49147219	0.869	NM_013359	ZNF221	zinc finger protein 221
chr19_-_49552638	0.846	NM_001083335 NM_013380	ZFP112	zinc finger protein 112 homolog (mouse)
chr1_+_40769877	0.821		ZNF684	zinc finger protein 684
chr9_+_135994734	0.789	NM_052821	WDR5	WD repeat domain 5
chr9_-_133945064	0.766	NM_004269	CRSP8P MED27	mediator complex subunit 27 pseudogene mediator complex subunit 27
chr9_-_129226312	0.757
chr14_-_19951417	0.732	NM_007110	TEP1	telomerase-associated protein 1
chr2_+_43854681	0.689	NM_001193464 NM_015522 NM_016008	DYNC2LI1	dynein, cytoplasmic 2, light intermediate chain 1
chr14_-_67232172	0.685	NM_016026	RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr19_+_17277476	0.676	NM_023937	MRPL34	mitochondrial ribosomal protein L34
chr19_+_42400908	0.651		ZNF383	zinc finger protein 383
chr7_+_89870647	0.642	NM_001185072 NM_001185073 NM_012129	CLDN12	claudin 12
chr14_+_22305570	0.634	NM_005015	OXA1L	oxidase (cytochrome c) assembly 1-like
chr18_-_42815965	0.627	NM_016427	TCEB3B	transcription elongation factor B polypeptide 3B (elongin A2)
chr9_-_133944877	0.625		MED27	mediator complex subunit 27
chr19_+_42099073	0.571	NM_198539	ZNF568	zinc finger protein 568
chr20_+_12937616	0.568	NM_018327	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr19_+_49337568	0.567		ZNF234	zinc finger protein 234
chr19_+_49337548	0.562	NM_001144824 NM_006630	ZNF234	zinc finger protein 234
chr17_-_18526296	0.555	NM_001145045	ZNF286B	zinc finger protein 286B
chr14_+_23700261	0.541	NM_006084	IRF9	interferon regulatory factor 9
chr1_+_38250953	0.534	NM_016037	UTP11L	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr5_+_145297490	0.533		SH3RF2	SH3 domain containing ring finger 2
chr11_+_65024889	0.532		MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr10_-_121345968	0.527		TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr3_+_58459131	0.518	NM_153331	KCTD6	potassium channel tetramerisation domain containing 6
chr8_-_145983457	0.517	NM_030580	ZNF34	zinc finger protein 34
chr1_+_40769819	0.504	NM_152373	ZNF684	zinc finger protein 684
chr16_+_52295545	0.492		FTO	fat mass and obesity associated
chr3_+_171422940	0.469		PRKCI	protein kinase C, iota
chr1_+_38250995	0.456		UTP11L	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr20_+_34019942	0.449	NM_080834	C20orf152	chromosome 20 open reading frame 152
chr19_-_49097774	0.445		LOC100505715	hypothetical LOC100505715
chr19_-_42098758	0.444	NM_001171979	ZNF829	zinc finger protein 829
chr2_-_85435074	0.438	NM_017750	RETSAT	retinol saturase (all-trans-retinol 13,14-reductase)
chr17_+_36636404	0.433	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr19_-_62782066	0.423		ZNF416	zinc finger protein 416
chr17_+_15543771	0.410		ZNF286A	zinc finger protein 286A
chr19_+_61798434	0.406	NM_021216	ZNF71	zinc finger protein 71
chr1_+_161305188	0.401	NM_005613	RGS4	regulator of G-protein signaling 4
chr7_+_47801413	0.398	NM_025031	PKD1L1 C7orf69	polycystic kidney disease 1 like 1 chromosome 7 open reading frame 69
chr1_+_54291847	0.397	NM_153035	TCEANC2	transcription elongation factor A (SII) N-terminal and central domain containing 2
chr19_+_49268106	0.384	NM_001037813	ZNF284	zinc finger protein 284
chr19_+_39587108	0.382	NM_032346	PDCD2L	programmed cell death 2-like
chr14_-_69953433	0.374	NM_018373	SYNJ2BP	synaptojanin 2 binding protein
chr19_+_62950001	0.373		ZNF776	zinc finger protein 776
chr17_-_17435631	0.359	NM_148172	PEMT	phosphatidylethanolamine N-methyltransferase
chr1_+_148137778	0.358	NM_016074	BOLA1	bolA homolog 1 (E. coli)
chr19_-_62781883	0.351	NM_017879	ZNF416	zinc finger protein 416
chr14_-_76958984	0.341	NM_138791 NM_001113475	C14orf148	chromosome 14 open reading frame 148
chr1_+_93418866	0.334		CCDC18	coiled-coil domain containing 18
chr17_+_36599664	0.324	NM_001190460	KRTAP9-1	keratin associated protein 9-1
chr15_-_81744469	0.320	NM_001717	BNC1	basonuclin 1
chr19_-_42098919	0.318	NM_001037232	ZNF829	zinc finger protein 829
chr1_+_161305558	0.316	NM_001113381	RGS4	regulator of G-protein signaling 4
chr4_+_130236731	0.313	NM_001099783	C4orf33	chromosome 4 open reading frame 33
chr10_-_98315090	0.310		TM9SF3	transmembrane 9 superfamily member 3
chr11_-_60880799	0.303	NM_001161452	CYBASC3	cytochrome b, ascorbate dependent 3
chr19_-_49500966	0.301	NM_004234	ZNF235	zinc finger protein 235
chr1_-_54291634	0.297	NM_004872	TMEM59	transmembrane protein 59
chr1_-_206125877	0.295
chr1_-_109420091	0.294	NM_005645	TAF13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr17_-_77616803	0.293		DUS1L	dihydrouridine synthase 1-like (S. cerevisiae)
chr15_+_40427592	0.292	NM_212465	CAPN3	calpain 3, (p94)
chr1_-_151788341	0.286	NM_002960	S100A3	S100 calcium binding protein A3
chr18_+_54958095	0.284	NM_033280	SEC11C	SEC11 homolog C (S. cerevisiae)
chr19_+_58715988	0.284	NM_018555	ZNF331	zinc finger protein 331
chr17_-_77616968	0.282	NM_022156	DUS1L	dihydrouridine synthase 1-like (S. cerevisiae)
chr19_+_62638474	0.280	NM_001023561	ZNF749	zinc finger protein 749
chr17_+_15543615	0.277	NM_001130842 NM_020652	ZNF286A	zinc finger protein 286A
chr16_+_52025874	0.271		RBL2	retinoblastoma-like 2 (p130)
chr9_+_15412875	0.269		SNAPC3	small nuclear RNA activating complex, polypeptide 3, 50kDa
chr2_+_165858586	0.267	NM_021007	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr6_+_139136349	0.264	NM_015439	CCDC28A	coiled-coil domain containing 28A
chr5_-_102926349	0.260	NM_031438	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12
chrX_+_48219344	0.259	NM_012280 NM_177439	FTSJ1	FtsJ homolog 1 (E. coli)
chr16_-_52295214	0.258	NM_001127897 NM_015272	RPGRIP1L	RPGRIP1-like
chr18_+_41938295	0.258	NM_138443	HAUS1	HAUS augmin-like complex, subunit 1
chr6_-_32892705	0.258	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr15_+_88696480	0.257	NM_001004309	ZNF774	zinc finger protein 774
chr3_-_152529999	0.254	NM_176894	P2RY13	purinergic receptor P2Y, G-protein coupled, 13
chr17_-_23721430	0.250		VTN	vitronectin
chr17_-_35464137	0.250		MED24	mediator complex subunit 24
chr19_+_45168872	0.250	NM_006503 NM_153001	PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr3_+_14141633	0.249		TMEM43	transmembrane protein 43
chr2_-_27739947	0.247	NM_014860	SUPT7L	suppressor of Ty 7 (S. cerevisiae)-like
chr19_+_17239264	0.247		BABAM1	BRISC and BRCA1 A complex member 1
chr5_+_57914658	0.244	NM_138453	RAB3C	RAB3C, member RAS oncogene family
chr3_+_14141583	0.243		TMEM43	transmembrane protein 43
chr9_-_114814286	0.243	NM_001101338	ZNF883	zinc finger protein 883
chr17_-_23721351	0.240		VTN	vitronectin
chr15_-_27901628	0.239		TJP1	tight junction protein 1 (zona occludens 1)
chr12_+_11694172	0.237		ETV6	ets variant 6
chr17_-_23721485	0.237	NM_000638	VTN	vitronectin
chr15_+_20384835	0.232	NM_001102610 NM_052903	TUBGCP5	tubulin, gamma complex associated protein 5
chr16_+_52025863	0.231		RBL2	retinoblastoma-like 2 (p130)
chr6_-_30766621	0.226	NM_007243	NRM	nurim (nuclear envelope membrane protein)
chr11_-_58368555	0.226	NM_145016	GLYATL2	glycine-N-acyltransferase-like 2
chr17_-_23721468	0.226		VTN	vitronectin
chr18_-_23019176	0.226	NM_031422	CHST9	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr17_-_77616953	0.222		DUS1L	dihydrouridine synthase 1-like (S. cerevisiae)
chr16_+_52025891	0.218		RBL2	retinoblastoma-like 2 (p130)
chr19_+_45194782	0.218	NM_178544	ZNF546	zinc finger protein 546
chr2_+_95195260	0.213		ZNF2	zinc finger protein 2
chr17_-_23721420	0.213		VTN	vitronectin
chr19_+_49455872	0.212	NM_181756	ZNF233	zinc finger protein 233
chr11_+_67130898	0.210	NM_001166102 NM_007103	NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr15_+_39853923	0.208	NM_001128608 NM_014994	MAPKBP1	mitogen-activated protein kinase binding protein 1
chr11_+_36572615	0.208	NM_138787	C11orf74	chromosome 11 open reading frame 74
chr11_+_72658586	0.208	NM_176798	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_+_105932536	0.205	NM_017752 NM_198881	TBC1D8B	TBC1 domain family, member 8B (with GRAM domain)
chr18_-_41938196	0.205	NM_001001937	ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr19_-_3752809	0.199	NM_002378	MATK	megakaryocyte-associated tyrosine kinase
chr5_+_178219519	0.198	NM_058230	ZNF354B	zinc finger protein 354B
chr19_+_62885148	0.198	NM_138347	ZNF551	zinc finger protein 551
chr10_-_131799051	0.196		LOC387723	hypothetical LOC387723
chr19_+_62949972	0.194	NM_173632	ZNF776	zinc finger protein 776
chr5_+_14493905	0.194		TRIO	triple functional domain (PTPRF interacting)
chr6_+_35812836	0.192	NM_145028	C6orf81	chromosome 6 open reading frame 81
chr1_-_33275051	0.192		AK2	adenylate kinase 2
chr21_-_35174742	0.191		RUNX1	runt-related transcription factor 1
chr17_-_44847215	0.190	NM_002634	PHB	prohibitin
chr7_+_98940537	0.189		ZKSCAN5	zinc finger with KRAB and SCAN domains 5
chr3_+_14141544	0.189		TMEM43	transmembrane protein 43
chrX_+_24621984	0.188	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr19_-_63205948	0.188		ZNF606	zinc finger protein 606
chr2_+_218843358	0.188	NM_001077399 NM_015488	PNKD	paroxysmal nonkinesigenic dyskinesia
chr19_-_49131250	0.188	NM_003425	ZNF45	zinc finger protein 45
chr19_-_63150825	0.188	NM_005773	ZNF256	zinc finger protein 256
chr16_+_52025845	0.187	NM_005611	RBL2	retinoblastoma-like 2 (p130)
chr1_-_33275039	0.185		AK2	adenylate kinase 2
chr19_+_17239148	0.184	NM_001033549 NM_014173	BABAM1	BRISC and BRCA1 A complex member 1
chr5_-_111120817	0.181	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr8_-_56848423	0.180	NM_152417	TMEM68	transmembrane protein 68
chr3_+_14141553	0.179		TMEM43	transmembrane protein 43
chr19_+_51804260	0.179		CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr7_+_128290162	0.178		ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr3_+_125586241	0.178		KALRN	kalirin, RhoGEF kinase
chr12_-_102413875	0.177	NM_198521 NM_001099336	C12orf42	chromosome 12 open reading frame 42
chr9_+_70161634	0.174	NM_021965	PGM5	phosphoglucomutase 5
chr12_-_47735373	0.173	NM_003482	MLL2	myeloid/lymphoid or mixed-lineage leukemia 2
chr3_+_171422908	0.172	NM_002740	PRKCI	protein kinase C, iota
chr1_-_33275015	0.172		AK2	adenylate kinase 2
chr16_-_20246309	0.171	NM_001007240 NM_001007241 NM_001007242 NM_001502	GP2	glycoprotein 2 (zymogen granule membrane)
chr11_-_133628348	0.163	NM_001037304 NM_001037305 NM_014174 NM_199297 NM_199298	THYN1	thymocyte nuclear protein 1
chr12_+_119224506	0.163	NM_012240	SIRT4	sirtuin 4
chr16_+_68542126	0.160	NM_001136214	CLEC18A	C-type lectin domain family 18, member A
chr19_+_49221333	0.159	NM_001129996 NM_013360	ZNF284 ZNF222	zinc finger protein 284 zinc finger protein 222
chr5_-_95184221	0.157	NM_001118890 NM_002064	GLRX	glutaredoxin (thioltransferase)
chr8_-_109330116	0.152	NM_001568	EIF3E	eukaryotic translation initiation factor 3, subunit E
chr1_-_3763620	0.150	NM_014704	KIAA0562	KIAA0562
chr17_+_36665161	0.150	NM_030975	KRTAP9-9	keratin associated protein 9-9
chr1_+_109827975	0.149	NM_153340	ATXN7L2	ataxin 7-like 2
chr2_-_230792844	0.148	NM_004509 NM_004510 NM_080424	SP110	SP110 nuclear body protein
chrX_+_77041612	0.148	NM_001866	COX7B	cytochrome c oxidase subunit VIIb
chr8_-_144770764	0.146		TSTA3	tissue specific transplantation antigen P35B
chr19_+_62972861	0.145		ZNF586	zinc finger protein 586
chr19_+_13090101	0.144	NM_052876	NACC1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_+_63669596	0.142	NM_005917	MDH1	malate dehydrogenase 1, NAD (soluble)
chr17_-_3740785	0.141	NM_172206	CAMKK1	calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr8_-_109330101	0.141		EIF3E	eukaryotic translation initiation factor 3, subunit E
chr1_-_145608965	0.140	NM_016361	ACP6	acid phosphatase 6, lysophosphatidic
chr4_+_109763119	0.138		RPL34	ribosomal protein L34
chr5_-_145542428	0.136	NM_020117	LARS	leucyl-tRNA synthetase
chr19_+_62554445	0.135	NM_020657	ZNF304	zinc finger protein 304
chr17_+_77910411	0.134	NM_207459	TEX19	testis expressed 19
chr3_+_199161446	0.133	NM_000996	RPL35A	ribosomal protein L35a
chr11_-_72182291	0.131	NM_006645	STARD10	StAR-related lipid transfer (START) domain containing 10
chr14_+_23175383	0.131	NM_005794 NM_182908	DHRS2	dehydrogenase/reductase (SDR family) member 2
chr1_-_25431544	0.129	NM_015484 NM_207170	SYF2	SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr15_+_39853982	0.129		MAPKBP1	mitogen-activated protein kinase binding protein 1
chr3_+_171422917	0.128		PRKCI	protein kinase C, iota
chr17_-_44847214	0.127		PHB	prohibitin
chr2_+_95194903	0.121	NM_001017396 NM_021088	ZNF2	zinc finger protein 2
chr19_-_49597594	0.119	NM_152354	ZNF285 ZFP112	zinc finger protein 285 zinc finger protein 112 homolog (mouse)
chr1_-_11041490	0.117		SRM	spermidine synthase
chr1_+_3763704	0.117	NM_004402	DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr2_-_84540096	0.115	NM_003849	SUCLG1	succinate-CoA ligase, alpha subunit
chr2_+_27740254	0.114		SLC4A1AP	solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr19_-_52045890	0.114	NM_004069 NM_021575	AP2S1	adaptor-related protein complex 2, sigma 1 subunit
chr19_+_49408523	0.114	NM_182490	ZNF227	zinc finger protein 227
chr8_+_27687821	0.112	NM_001017420	ESCO2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr11_-_100959868	0.111	NM_004621	TRPC6	transient receptor potential cation channel, subfamily C, member 6
chr10_-_38305458	0.111	NM_145011	ZNF25	zinc finger protein 25
chr3_+_14141440	0.110	NM_024334	TMEM43	transmembrane protein 43
chr1_+_17571277	0.109	NM_207421	PADI6	peptidyl arginine deiminase, type VI

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.81	1.25e-03	GO:0006355	regulation of transcription, DNA-dependent
1.74	4.60e-03	GO:0051252	regulation of RNA metabolic process
1.56	4.79e-03	GO:0080090	regulation of primary metabolic process
1.71	5.48e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.54	8.54e-03	GO:0031323	regulation of cellular metabolic process
1.63	1.01e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.66	1.01e-02	GO:0010468	regulation of gene expression
1.55	1.13e-02	GO:0060255	regulation of macromolecule metabolic process
1.66	1.34e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.61	2.33e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61	2.33e-02	GO:0031326	regulation of cellular biosynthetic process
1.47	2.86e-02	GO:0019222	regulation of metabolic process
1.59	3.38e-02	GO:0009889	regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.31	1.31e-07	GO:0043229	intracellular organelle
1.31	1.62e-07	GO:0043226	organelle
1.52	4.10e-07	GO:0005634	nucleus
1.34	6.85e-07	GO:0043231	intracellular membrane-bounded organelle
1.34	7.67e-07	GO:0043227	membrane-bounded organelle
1.21	7.06e-05	GO:0044424	intracellular part
1.20	1.08e-04	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.07	1.77e-07	GO:0008270	zinc ion binding
1.97	3.25e-07	GO:0003677	DNA binding
1.92	1.88e-06	GO:0046914	transition metal ion binding
1.63	1.16e-04	GO:0003676	nucleic acid binding
1.54	3.24e-04	GO:0046872	metal ion binding
1.52	5.54e-04	GO:0043169	cation binding
1.51	6.22e-04	GO:0043167	ion binding